API Reference
All /v1/* endpoints require a Bearer token. Get a free key on the Dashboard or try live calls in the Playground.
Create a free API key. Returns the key once — store it securely. Submitting the same email twice returns 409.
| Field | Type | Description | |
|---|---|---|---|
email | string | required | Your email. Used as the unique account identifier. |
curl -X POST https://your-domain.com/v1/keys/signup \ -H "Content-Type: application/json" \ -d '{"email": "you@example.com"}'
{
"api_key": "rxb_a3f2d...",
"email": "you@example.com",
"tier": "free",
"monthly_quota": 500
}
Normalize messy drug free-text to a canonical RxNorm RXCUI, NDC, dosage form, and strength. Handles misspellings, abbreviations (HCTZ, MetXR, Coumadin), and free-text dose noise. Returns the best match with confidence score plus ranked alternates.
| Field | Type | Description | |
|---|---|---|---|
text | string | required | Free-text drug string, e.g. "metformn 500 tab", "HCTZ 25", "Coumadin 5mg" |
curl -X POST https://your-domain.com/v1/normalize \ -H "Authorization: Bearer rxb_your_key" \ -H "Content-Type: application/json" \ -d '{"text": "metformn 500 tab"}'
{
"query": "metformn 500 tab",
"match": {
"rxcui": "861007",
"ndc": "00093-7214-01",
"ingredient": "metformin",
"brand": "Glucophage",
"dosage_form": "tablet",
"strength": "500 mg",
"description": "Metformin is an oral diabetes medicine...",
"description_source": "rxbridge_curated",
"confidence": 0.92
},
"alternatives": [...]
}
Look up all catalog entries for a given RxNorm RXCUI, including lay-level patient description.
| Field | Type | Description | |
|---|---|---|---|
rxcui | path param | required | RxNorm Concept Unique Identifier, e.g. 861007 |
curl https://your-domain.com/v1/drug/861007 \ -H "Authorization: Bearer rxb_your_key"
{
"rxcui": "861007",
"description": "Metformin is an oral diabetes medicine that helps control blood sugar...",
"results": [
{ "rxcui": "861007", "ingredient": "metformin", "brand": "Glucophage",
"dosage_form": "tablet", "strength": "500 mg" }
]
}
Check drug-drug interaction evidence for 2–10 drugs. Returns severity-tagged evidence objects sourced from FDA drug labels. Framed strictly as evidence — not clinical verdicts. Every response includes a mandatory disclaimer field.
| Field | Type | Description | |
|---|---|---|---|
drugs | string[] | required | 2–10 drug texts or RXCUIs, e.g. ["warfarin 5mg", "aspirin 81mg"] |
curl -X POST https://your-domain.com/v1/interactions \ -H "Authorization: Bearer rxb_your_key" \ -H "Content-Type: application/json" \ -d '{"drugs": ["warfarin 5mg", "aspirin 81mg"]}'
{
"resolved": [
{ "query": "warfarin 5mg", "rxcui": "855332", "ingredient": "warfarin" },
{ "query": "aspirin 81mg", "rxcui": "1191", "ingredient": "aspirin" }
],
"interactions": [
{
"drug_pair": ["warfarin", "aspirin"],
"severity": "major",
"summary": "Aspirin can potentiate warfarin's anticoagulant effect...",
"evidence": {
"source_label": "Coumadin (warfarin) FDA label",
"source_section": "Drug Interactions (Section 7)",
"snippet": "Aspirin inhibits platelet aggregation..."
}
}
],
"disclaimer": "EVIDENCE ONLY — not medical advice..."
}
The combined one-call endpoint. Accepts messy drug text (single string or list), normalizes each to canonical RXCUI + dosage form + lay description, then cross-checks all drug pairs for severity-tagged interaction evidence — all in a single request. This is the wedge.
| Field | Type | Description | |
|---|---|---|---|
text | string | optional | Single drug free-text. Provide either text or medications. |
medications | string[] | optional | List of up to 10 drug strings. Used for multi-drug interaction check. |
curl -X POST https://your-domain.com/v1/medication \ -H "Authorization: Bearer rxb_your_key" \ -H "Content-Type: application/json" \ -d '{"medications": ["metformn 500 tab", "lisinprl 10mg", "atorvastn 40"]}'
{
"medications": [
{
"input": "metformn 500 tab",
"resolved": true,
"confidence": 0.92,
"match": {
"rxcui": "861007",
"ingredient": "metformin",
"brand": "Glucophage",
"dosage_form": "tablet",
"strength": "500 mg",
"description": "Metformin is an oral diabetes medicine..."
}
}
],
"interactions": [],
"disclaimer": "EVIDENCE ONLY — not medical advice..."
}
Returns current monthly usage and quota for the authenticated key, with a per-endpoint breakdown.
curl https://your-domain.com/v1/usage \ -H "Authorization: Bearer rxb_your_key"
{
"email": "you@example.com",
"tier": "free",
"usage": 14,
"limit": 500,
"remaining": 486,
"period": "2026-06",
"by_endpoint": {
"/v1/normalize": 8,
"/v1/medication": 6
}
}
RxBridge is a developer API for evidence aggregation. Interaction data is sourced from FDA drug labels (openFDA). Not a clinical decision support system — do not present interaction evidence as patient-facing verdicts without independent clinical validation.